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Search BioGRID for SARS-CoV-2 Protein Interactions | Download SARS-CoV-2 and Coronavirus-Related Interactions
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BioGRID ORCS - An open repository of CRISPR screens
The BioGRID Open Respository of CRISPR Screens (ORCS) is a publicly accessible database of CRISPR screens compiled through comprehensive curation efforts.
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The Kinase and Phosphatase Interactome in S. cerevisiae Curation Project
This BioGRID project page is designed to allow exploration of the entire yeast kinome and its interactions, including genetic interactions and all mapped sites of protein phosphorylation.
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Gene Info eXtension (GIX)
GIX is a browser extension that allows you to retrieve information about a gene product directly on any webpage simply by double clicking an official gene name, synonym or supported accession.
Latest News
COVID-19 is a rapidly evolving global health crisis and BioGRID is expediting release of new datasets for SARS-CoV-2, SARS-CoV, and MERS-CoV to help facilitate new therapeutic approaches. The BioGRID's curated set of Coronavirus-related data have been updated to include interactions from 143 publications and preliminary reports. These additions bring our total number of Coronavirus-related interactions to 3,429 including 2,177 interactions from 45 publications and preliminary reports for SARS-CoV-2 (COVID-19). To download all coronavirus-related interaction data in BioGRID, visit our download page. For more information on BioGRID curation of SARS-CoV-2 (COVID-19) and related Coronaviruses, check out our wiki.
If you have interaction data for SARS-CoV-2 (or other Coronavirus-related data) that you'd like to deposit directly into the BioGRID Database, please contact us at biogridadmin@gmail.com.
![BioGRID Build 3.5.188 includes 3,429 Coronavirus-related Interactions](http://uahbt.jiuhongwang.com/images/twitter/biogrid_coronavirus_datasett.png)
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 72,826 publications. These additions bring our total number of non-redundant interactions to 1,472,343, raw interactions to 1,881,423, non-redundant chemical associations to bluelight安卓版, raw chemical associations to 28,093, Non-Redundant PTM Sites to 458,181, Raw PTM Sites to 817,400 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our bluelight安卓版.
COVID-19 is a rapidly evolving global health crisis and BioGRID is expediting release of new datasets for SARS-CoV-2, SARS-CoV, and MERS-CoV to help facilitate new therapeutic approaches. The BioGRID's curated set of Coronavirus-related data have been updated to include interactions from 142 publications and preliminary reports. These additions bring our total number of Coronavirus-related interactions to 2,796 including blue灯下载 interactions from 44 publications and preliminary reports for SARS-CoV-2 (COVID-19). To download all coronavirus-related interaction data in BioGRID, visit our download page. For more information on BioGRID curation of SARS-CoV-2 (COVID-19) and related Coronaviruses, check out our wiki.
If you have interaction data for SARS-CoV-2 (or other Coronavirus-related data) that you'd like to deposit directly into the BioGRID Database, please contact us at biogridadmin@gmail.com.
![bluelight安卓版](http://uahbt.jiuhongwang.com/images/twitter/biogrid_coronavirus_datasett.png)
The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 72,637 publications. These additions bring our total number of non-redundant interactions to 1,469,992, raw interactions to 1,878,317, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 458,181, Raw PTM Sites to 817,400 and Un-Assigned PTMs to bluelight翻墙.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
The latest update of BioGRID (build 3.5.186) adds 52,000+ new human two-hybrid interactions from the study "A reference map of the human binary protein interactome" by Luck K et al (Nature, April 2023). This human reference interactome (HuRI) contains high throughput protein interactions that may be integrated with genome, transcriptome and proteome data in order to study the function of proteins within different physiological and pathological cellular contexts. The data for this publication can also be accessed and downloaded online at the The Human Reference Protein Interactome Mapping Project.
A special thanks to all authors of the study: Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Cote AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovacs IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, Simonovsky E, Ta?an M, Tejeda A, Tropepe V, Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP and Calderwood MA
If you have interaction data you'd like to deposit directly into the BioGRID Database, please contact us at biogridadmin@gmail.com.
![Featured Dataset: 52,000+ new Two-Hybrid interactions for Human from Luck K et al. (2023)](http://uahbt.jiuhongwang.com/images/twitter/biogrid_featured_dataset.png)
The latest update of BioGRID (build 3.5.186) adds 27,000+ new mouse co-fractionation interactions from the study "blue room living room interior. Modern home with lamp and ...:Blue room living room interior. Modern home with lamp and armchair. luxury living room corner style._提供1亿正版图片,字体,音乐,在线购买和永久RF授权服务" by Pourhaghighi R et al (Cell Syst., April 2023). To elucidate the protein interactions underlying normal neuron function in the mammalian brain, the authors performed a comprehensive multi-dimensional biochemical fractionation assay, surveying endogenous macromolecules across the adult mouse brain and providing a global interactome.
A special thanks to all authors of the study: Pourhaghighi R, Ash PEA, Phanse S, Goebels F, Hu LZM, Chen S, Zhang Y, Wierbowski SD, Boudeau S, Moutaoufik MT, Malty RH, Malolepsza E, Tsafou K, Nathan A, Cromar G, Guo H, Abdullatif AA, Apicco DJ, Becker LA, Gitler AD, Pulst SM, Youssef A, Hekman R, Havugimana PC, White CA, Blum BC, Ratti A, Bryant CD, Parkinson J, Lage K, Babu M, Yu H, Bader GD, Wolozin B, and Emili A
If you have interaction data you'd like to deposit directly into the BioGRID Database, please contact us at biogridadmin@gmail.com.
![Featured Dataset: 27,000+ new co-fractionation interactions for mouse from Pourhaghighi R et al. (2023)](http://uahbt.jiuhongwang.com/images/twitter/biogrid_featured_dataset.png)
COVID-19 is a rapidly evolving global health crisis and BioGRID is expediting release of new datasets for SARS-CoV-2, SARS-CoV, and MERS-CoV to help facilitate new therapeutic approaches. The BioGRID's curated set of Coronavirus-related data have been updated to include interactions from 123 publications and preliminary reports. These additions bring our total number of Coronavirus-related interactions to 967 including 414 interactions from 36 publications and preliminary reports for SARS-CoV-2 (COVID-19). To download all coronavirus-related interaction data in BioGRID, visit our download page. For more information on BioGRID curation of SARS-CoV-2 (COVID-19) and related Coronaviruses, check out our wiki.
If you have interaction data for SARS-CoV-2 (or other Coronavirus-related data) that you'd like to deposit directly into the BioGRID Database, please contact us at biogridadmin@gmail.com.
![BioGRID Build 3.5.186 includes 967 Coronavirus-related Interactions](http://uahbt.jiuhongwang.com/images/twitter/biogrid_coronavirus_datasett.png)
The bluelight翻墙's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 72,408 publications. These additions bring our total number of non-redundant interactions to blue lamp下载, raw interactions to 1,871,024, non-redundant chemical associations to 12,015, raw chemical associations to 28,093, Non-Redundant PTM Sites to 458,181, Raw PTM Sites to 817,400 and Un-Assigned PTMs to 57,396.
New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.
BioGRID update 3.5.185 includes a comprehensive update to our Schizosaccharomyces pombe dataset in partnership with The Scientific Resource for Fission Yeast (PomBase). This update incorporates more than 900 new interactions. Moreover, this increases the total number of Schizosaccharomyces pombe interactions deposited in BioGRID to 79,863 from 2,874 publications. These interactions and all associated meta data are available immediately online via all standard BioGRID searches and bluelight翻墙. You can also find these and many additional fission yeast resources available at http://www.pombase.org.
A special thanks to the PomBase Team for their tireless curation efforts and in particular Antonia Lock, Kim Rutherford and Valerie Wood for directly helping to facilitate the BioGRID collaboration.
If you have an interaction dataset you'd like to deposit directly into the BioGRID, please contact us at biogridadmin@gmail.com.
![bluelight安卓版](http://uahbt.jiuhongwang.com/images/twitter/pombase-large.jpg)
COVID-19 is a rapidly evolving global health crisis and BioGRID is expediting release of new datasets for SARS-CoV-2, SARS-CoV, and MERS-CoV to help facilitate new therapeutic approaches. The BioGRID's curated set of Coronavirus-related data have been updated to include interactions from 66 publications and preliminary reports. These additions bring our total number of Coronavirus-related interactions to 743 including 367 interactions from 19 publications and preliminary reports for SARS-CoV-2 (COVID-19). To download all coronavirus-related interaction data in BioGRID, visit our download page. For more information on BioGRID curation of SARS-CoV-2 (COVID-19) and related Coronaviruses, check out our wiki.
If you have interaction data for SARS-CoV-2 (or other Coronavirus-related data) that you'd like to deposit directly into the BioGRID Database, please contact us at biogridadmin@gmail.com.
![BioGRID Build 3.5.185 includes 743 Coronavirus-related Interactions](http://uahbt.jiuhongwang.com/images/twitter/biogrid_coronavirus_datasett.png)
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